Neurodevelopmental disorders such as Autism Spectrum Disorders, xx, and xx are complex, multi-faceted problems that affect many lives. The models and experimental approaches used to understand them are constantly being developed, and much improvement must still be made today. In recent years, however, a multidisciplinary toolbox has emerged that includes new investigatory protocols, imaging methods, and analysis techniques.
High Resolution Optical Imaging
As experimental techniques improve, imaging and recording methods must be developed to allow for the realization of conclusive results. In vivo imaging in particular poses a distinct challenge due to inherent limitations. However, two-photon and three-photon imaging, paired with enhanced tagging (e.g. for calcium imaging) has allowed us to visualize the inner workings of the brain in greater resolution than ever before.